Luigi Gnudi Selected Research

Mitochondrial DNA (mtDNA)

1/2020	A case for measuring both cellular and cell-free mitochondrial DNA as a disease biomarker in human blood.
12/2015	Altered circulating mitochondrial DNA and increased inflammation in patients with diabetic retinopathy.
6/2015	Altered Mitochondrial Function, Mitochondrial DNA and Reduced Metabolic Flexibility in Patients With Diabetic Nephropathy.

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Luigi Gnudi Research Topics

Disease

16	Diabetic Nephropathies (Diabetic Nephropathy) 07/2023 - 03/2005
10	Type 2 Diabetes Mellitus (MODY) 01/2023 - 06/2010
9	Albuminuria 01/2023 - 08/2007
7	Chronic Renal Insufficiency 01/2023 - 03/2010
7	Kidney Diseases (Kidney Disease) 01/2022 - 08/2008
7	Inflammation (Inflammations) 01/2020 - 08/2008
6	Hypertension (High Blood Pressure) 01/2019 - 07/2003
5	Fibrosis (Cirrhosis) 01/2021 - 08/2007
3	Insulin Resistance 06/2023 - 02/2016
3	Cardiovascular Diseases (Cardiovascular Disease) 11/2021 - 06/2013
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 06/2015
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019 - 01/2017
2	Vascular Remodeling 03/2024 - 01/2019
2	Hypertrophy 01/2019 - 05/2014
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/2023
1	Cardio-Renal Syndrome 09/2021
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Atherosclerosis 01/2017
1	Diabetes Mellitus 02/2016
1	Hyperglycemia 12/2015
1	Diabetic Retinopathy (Retinopathy, Diabetic) 12/2015
1	Ulcer 10/2015
1	Diabetic Foot 10/2015
1	Renal Insufficiency (Renal Failure) 06/2015
1	Mood Disorders (Mood Disorder) 05/2015
1	Anxiety Disorders (Anxiety Disorder) 05/2015
1	Obesity 01/2013
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2013
1	Glucose Intolerance 01/2012
1	Weight Gain 06/2010
1	Cough 06/2010

Drug/Important Bio-Agent (IBA)

8	Glucose (Dextrose)FDA LinkGeneric 04/2023 - 04/2006
4	Proteins (Proteins, Gene)FDA Link 03/2024 - 08/2007
4	Hormones (Hormone)IBA 07/2023 - 01/2017
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2021 - 08/2007
4	nephrinIBA 01/2010 - 08/2007
3	Insulin (Novolin)FDA Link 06/2023 - 06/2010
3	Calcitriol (Calcijex)FDA LinkGeneric 01/2023 - 01/2023
3	LipidsIBA 01/2021 - 03/2010
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2013
3	Mitochondrial DNA (mtDNA)IBA 01/2020 - 06/2015
2	SodiumIBA 04/2023 - 11/2016
2	Vitamin D FDA LinkGeneric 01/2023 - 01/2023
2	Sodium-Glucose Transporter 2 InhibitorsIBA 11/2021 - 01/2016
2	AngiopoietinsIBA 09/2021 - 01/2016
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2021 - 11/2020
2	Pharmacological BiomarkersIBA 11/2020 - 12/2019
2	AlbuminsIBA 01/2019 - 03/2010
2	Oxidants (Oxidizing Agents)IBA 01/2018 - 05/2014
2	Streptozocin (Streptozotocin)FDA Link 01/2018 - 01/2010
2	AntioxidantsIBA 01/2017 - 05/2014
2	erucylphosphocholineIBA 05/2015 - 01/2012
2	Angiopoietin-1IBA 01/2014 - 08/2008
2	CreatinineIBA 11/2013 - 08/2007
2	Rosiglitazone (Avandia)FDA Link 02/2013 - 01/2010
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 10/2008 - 07/2003
1	CholesterolIBA 06/2023
1	Glucagon-Like Peptide 1 (GLP 1)IBA 04/2023
1	Mineralocorticoid Receptor AntagonistsIBA 04/2023
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2023
1	MineralsIBA 01/2023
1	CalciumIBA 01/2023
1	Phosphates (Orthophosphate)IBA 01/2023
1	dapagliflozinIBA 01/2022
1	fibroblast growth factor 21IBA 01/2021
1	Urea (Carbamide)FDA LinkGeneric 01/2021
1	insulin receptor-related receptor (IRR)IBA 01/2019
1	Protein Isoforms (Isoforms)IBA 01/2019
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2019
1	Mitogen-Activated Protein KinasesIBA 01/2018
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2018
1	JNK Mitogen-Activated Protein KinasesIBA 01/2018
1	Annexin A1IBA 01/2018
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	Antihypertensive Agents (Antihypertensives)IBA 01/2017
1	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2016
1	Nitric Oxide Synthase (NO Synthase)IBA 05/2014
1	CollagenIBA 05/2014
1	Calcitonin Gene-Related PeptideIBA 05/2014
1	Angiotensin IIIBA 05/2014
1	Valsartan (Vals)FDA Link 11/2013
1	Amlodipine (Norvasc)FDA LinkGeneric 11/2013
1	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 11/2013
1	Testosterone (Sustanon)FDA Link 06/2013
1	Amiloride (Midamor)FDA LinkGeneric 02/2013
1	2,4-thiazolidinedione (thiazolidinedione)IBA 02/2013
1	Spironolactone (Aldactone)FDA LinkGeneric 02/2013
1	TRPV1 receptorIBA 01/2013
1	AdipokinesIBA 01/2013
1	Pioglitazone (Actos)FDA Link 01/2012
1	Insulin Glargine (Lantus)FDA Link 06/2010
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2010
1	CytokinesIBA 10/2008
1	ImmunosorbentsIBA 10/2008
1	EnzymesIBA 10/2008

Therapy/Procedure

12	Therapeutics 11/2021 - 08/2008
1	Investigational Therapies (Experimental Therapy) 01/2019
1	Lasers (Laser) 10/2015
1	Subcutaneous Injections 06/2010
1	Secondary Prevention 03/2010